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Journal Article 1 Mention
Reevaluating vitamin A for measles management in high-income settings
Parminder S. Suchdev2025
Nancy F. KrebsSherry A. Tanumihardjo
Few Citations
1 citations · Public Health, Environmental and Occupational Health
Open Access

TLDR

Giving vitamin A to every child with measles in the U.S. is not needed and could be risky. Only kids at higher risk should get it, and always with a doctor's guidance.

Summary

1 Study Aim

The paper aims to question the current U.S. practice of giving vitamin A supplements to all children with measles. The authors want to see if this universal approach is still needed in high-income countries like the United States, where vitamin A deficiency is rare. They suggest that only certain high-risk children should get vitamin A, to avoid unnecessary risks. Simply put: The paper asks if all kids with measles in the U.S. really need vitamin A, or just those who are most at risk.

2 Study Design

This work is a review and expert commentary, not a new experiment. The authors analyze existing research, guidelines, and recent measles data in the United States. They compare evidence from countries with high and low rates of vitamin A deficiency. The paper also discusses findings from a recent study in Italy and uses national nutrition survey data to support its arguments. Simply put: The authors looked at past studies and health data to see if giving vitamin A to all kids with measles in the U.S. makes sense.

3 Findings

The authors report that vitamin A deficiency is very rare in the U.S., and most children already get enough or even too much vitamin A from food and supplements. They highlight that giving vitamin A to all children with measles, as currently recommended, may not help and could cause harm, such as vitamin A toxicity. The paper points out that studies from high-income countries show no clear benefit from universal supplementation. Instead, the authors recommend giving vitamin A only to children at higher risk, such as those who are hospitalized, very young, malnourished, immunocompromised, or showing signs of deficiency. They urge health agencies to update their guidelines and stress that vaccination is the best way to prevent measles. Simply put: The paper finds that only some kids with measles in the U.S. need vitamin A, and giving it to everyone could do more harm than good.

Abstract

As of June 24, 2025, a total of 1227 confirmed measles cases were reported across the United States-a concerning development given that the country achieved measles elimination in 2000. 1 This resurgence of a vaccine-preventable illness has renewed attention to clinical management strategies, including vitamin A supplementation.While U.S. public health authoritiesincluding the Centers for Disease Control and Prevention (CDC), the American Academy of Pediatrics (AAP), and the National Foundation for Infectious Diseases (NFID)-recommend routine vitamin A supplementation for all children with measles, we present evidence challenging this universal approach.Instead, we propose a targeted strategy focused on high-risk subgroups, given the low prevalence of vitamin A deficiency and the potential risks of toxicity in the U.S. context.

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