Review 1 Mention
A systematic review and meta-analysis of 90 cohort studies of social isolation, loneliness and mortality
Fan Wang•2023
Yu GaoZhen Han
Top 1% · 100th Percentile
452 citations · Health

TLDR

People who have little contact with others or often feel lonely are more likely to die earlier. Strengthening social connections may be an important part of protecting health.

Summary

1 Study Aim

The study aimed to assess whether social isolation (objectively limited contact with others) and loneliness (the personal feeling of lacking meaningful connection) are linked with mortality. The authors also compared the strength and consistency of these relationships across available cohort studies. The researchers wanted to determine whether weak social ties and feeling alone are connected with a higher chance of dying.

2 Study Design

The researchers conducted a systematic review (a structured search and evaluation of existing studies) and meta-analysis (a statistical combination of results). They included 90 prospective cohort studies (studies that follow people forward over time). These studies examined adults’ social isolation or loneliness and later mortality. The researchers compared mortality among people with different levels of social connection and assessed differences across studies. The researchers combined evidence from 90 studies that tracked people over time to examine whether social disconnection predicted death.

3 Findings

The study found significant associations between both social isolation and loneliness and higher all-cause mortality (death from any cause). Pooled estimates indicated about 32% higher mortality with social isolation and about 14% higher mortality with loneliness. The cited findings also report associations with cancer and cardiovascular mortality, particularly for social isolation. The authors argue that social disconnection should be recognized as an important public-health concern, while noting that these observational results do not prove causation. People who are socially disconnected or lonely face a higher risk of dying, so health efforts should pay attention to social connection as well as physical health.

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