Journal Article 1 Mention
Measles in paediatric patients in Poland – a 3-year retrospective single-centre study
Maciej Stępień2024
Martyna CholewikMagdalena Eksmond
Low Citations · 14th Percentile
0 citations · Epidemiology
Open Access

TLDR

Measles caused fever and rash in every hospitalized child studied. Lung and ear infections were common, while babies showed different symptoms and had more ear infections than older children.

Summary

1 Study Aim

The authors aimed to describe measles symptoms and complications in hospitalized children. They especially examined whether infants under 13 months differed from older children. The study examined how measles appeared in babies compared with older children.

2 Study Design

The researchers conducted a retrospective observational study (a study reviewing past medical records without changing treatment). They examined records from children hospitalized with measles at one Polish center between January 2017 and December 2019. The sample included 84 children, with 26 infants under 13 months and 58 older children. The researchers compared symptoms, complications, vaccination histories, and antibiotic use between the age groups. The researchers reviewed hospital records from 84 children and compared babies with older children.

3 Findings

The study reports that 67 of 84 children had no recorded measles vaccination; 28 were too young to receive it. Fever and erythema (skin redness) occurred in every child. Pneumonia (lung infection) affected 39 children, while acute otitis media (middle-ear infection) affected 19. Infants had less photophobia (discomfort from bright light), lymphadenopathy (swollen lymph nodes), hepatomegaly (enlarged liver), and splenomegaly (enlarged spleen). They had more acute otitis media than older children. These age-related differences support age-aware assessment of hospitalized children with measles. Unvaccinated children made up most cases, and babies were more likely to develop ear infections.

Abstract

Introduction: Measles is a highly contagious viral disease.In recent years, there has been an alarming increase in measles cases in Europe.Most patients were not vaccinated.The aim of this study was to analyse the clinical manifestation of measles in paediatric patients, considering the differences between infants and older children.Material and methods: This was a retrospective observational study, for which data were collected from the medical records of paediatric patients hospitalised due to measles January 2017 -December 2019.Stratification was based on age.In the younger group (infants), children under 13 months of age were included.Results: In total 84 children were enrolled in the study, including 26 infants (30.95%) and 58 older children (69.5%).In 67/84 (79.76%) participants no history of measles vaccination was reported.Among those not vaccinated, there were 28/67 (41.79%) children too young for vaccination.Fever and erythema occurred in all patients.The disease was complicated by pneumonia in 39/84 (46.43%) and acute otitis media in 19/84 (22.62%) children.Antibiotics were administered in 45/84 (69.05%) cases, of which 10/58 (17.24%) had 2 or more.The infants had significantly less frequent photophobia (p = 0.041693), lymphadenopathy (p = 0.005229), hepatomegaly (p = 0.030619), and splenomegaly (p = 0.019469), Instead, they were significantly more likely to have acute otitis media (p = 0.020141).Conclusions: Measles is a serious disease that most commonly affects unvaccinated children.The most common symptoms include fever and rash.Otitis media and pneumonia were the most common measles complications.The variations in symptoms and complications of measles differ significantly between infants and older children.

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