Journal Article 1 Mention
Changes in Brain-Health Related Modifiable Risk Factors in Older Adults After One Year of COVID-19-Restrictions
Lisa Waterink2022
Els D. BakkerLeonie N.C. Visser
Top 17% · 83rd Percentile
15 citations · Neurology
Open Access

TLDR

After a year of restrictions, many older adults felt lonelier, slept worse, and exercised less. However, many also exercised more, ate better, or drank less, showing that support should target people most affected.

Summary

1 Study Aim

The study aimed to describe changes in eight modifiable brain-health factors (changeable habits and conditions linked with brain health) after one year of COVID-19 restrictions. It also examined whether personal characteristics, subjective memory complaints (personally noticed memory problems), and COVID-19 experiences were linked with harmful or helpful changes. The authors intended these results to guide targeted health education and prevention. The study examined how restrictions changed older adults’ daily habits and which people experienced the greatest difficulties.

2 Study Design

The authors conducted a population-based cross-sectional study (a one-time assessment) using an online survey. They invited 17,773 Dutch Brain Research Registry members aged 50 or older without self-reported mild cognitive impairment or dementia. Of these, 3,943 participants completed the survey in February or March 2021. Questions covered physical activity, sleep, memory decline, stress, loneliness, diet, alcohol, and smoking. Researchers counted harmful and helpful changes and used negative binomial regression (a method for analyzing counts) to test related characteristics. They also assessed the LIBRA score (LIfestyle for BRAin health, a measure of modifiable dementia-risk factors) in 1,984 participants. Responses were self-reported and retrospective. The survey provided a large snapshot of reported habit changes during the pandemic.

3 Findings

The study found that 72.3% of participants reported at least one harmful change, while 60.5% reported at least one helpful change. Loneliness, sleep problems, and reduced physical activity were the most common harmful changes. Increased physical activity, healthier eating, and reduced alcohol use were the most common helpful changes. Younger participants, women, people living alone or in cities, and those less satisfied with income reported more harmful changes. Subjective memory complaints, past or current infection, and fear of infection showed similar associations. Participants with higher LIBRA scores also reported more harmful changes. The authors recommend targeted education, lifestyle support, and monitoring during restrictions. They caution that the volunteer sample was mainly female and highly educated. Restrictions affected habits in both directions, but support should prioritize people reporting more difficulties.

Abstract

Background: The COVID-19 pandemic has major influence on lifestyle and mental health, which might affect brain-health and increase the risk of cognitive decline, particularly in older adults. We aimed to describe changes in modifiable risk factors related to brain-health in older adults after one year of COVID-19 restrictions. Methods: An online survey was disseminated between February and March 2021 to 17,773 registrants of the Dutch Brain Research Registry, aged ≥50, without a self-reported diagnosis of mild cognitive impairment or dementia. Participants were asked to report potential changes in behaviors during the COVID-19 pandemic, compared to pre-pandemic, in eight domains related to brain health: physical activity, sleep, feeling of memory decline, perceived stress, feeling of loneliness, diet, alcohol consumption, and smoking. We used negative binomial regression analyses to relate (socio)demographics, subjective memory complaints and COVID-19 related aspects (fear of, or current/past COVID-19 infection) to the number of reported detrimental and beneficial changes as dependent variable. Results: 3,943 participants (66 ± 8 years old; 76% female; 71% highly educated) completed the survey. After one year of COVID-19-restrictions, 74% reported at least one detrimental lifestyle change unfavorable for their brain health, most frequently reported were feelings of loneliness, sleep problems, and less physical activity. 60% of participants reported at least one beneficial change, which were most often more physical activity, healthier dietary habits, and less alcohol consumption. Individuals who are younger [incidence rate ratio (IRR) = 0.99, 95% CI = 0.98-0.99], female (1.20, 1.11-1.30), living alone (1.20, 1.11-1.28) and in urban environments (1.18, 1.08-1.29), who are less satisfied with their income (1.38, 1.17-1.62), experiencing subjective memory complaints (1.40, 1.28-1.52) and those with a past or current (1.19, 1.06-1.34) or fear of a COVID-19 infection (1.33, 1.25-1.42) reported higher numbers of detrimental changes. Discussion: The COVID-19 pandemic has influenced lifestyle in both positive and negative ways. We identified (socio)demographic factors associated with more detrimental changes in modifiable risk factors related to brain health, suggesting that some individuals are more vulnerable for the impact of the COVID-19 pandemic. These findings provide an opportunity for targeted prevention and education to promote a healthy lifestyle during and after the pandemic.

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