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Feyisayo O Oguntuase, Okelue E Okobi, Ogunsemi Olawale | Cureus | (2025)
Key Takeaways
Plain English Takeaway
More people in the U.S. are using prescription medicine for depression, especially women, older adults, and those with disabilities or less money. Some groups, like White people, use these medicines more than others.
Study Aim
The main goal of this study is to examine how the use of prescription antidepressant medications for depression symptoms has changed in the United States from 2019 to 2023. The research specifically looks at differences in medication use based on age, gender, race, and social vulnerability (meaning how much a person's social situation makes them more at risk for problems). The study aims to help doctors and policymakers understand who is using these medicines most and where there are gaps in care.
Simply put: The study wants to find out who is taking depression medicine in the U.S. and how this has changed over five years.
Study Design
The researchers used data from the National Health Interview Survey (NHIS), which is a yearly survey of U.S. households. They analyzed responses from adults aged 18 and older who answered questions about feeling depressed and whether they used prescription medicine for these symptoms between 2019 and 2023. The study included about 14,820 people who reported depression symptoms and medication use. The team looked at trends by age, gender, race, income, insurance, disability, and social vulnerability (measured by the CDC Social Vulnerability Index, which ranks how much people are at risk due to social factors). They used statistical methods to make sure the results represent the whole country.
Simply put: The study looked at survey answers from thousands of adults to see who uses depression medicine, breaking it down by age, gender, race, and other factors.
Findings
The study reveals that antidepressant use in the U.S. increased from 9.8% in 2019 to 11.4% in 2023. Women used these medicines much more than men, and older adults had higher rates than younger ones. White individuals had the highest use, while Black and Asian groups had lower rates. People with disabilities were much more likely to use antidepressants than those without disabilities. Those with lower incomes and public insurance (like Medicaid) also had higher usage. The study highlights ongoing gaps, showing that some groups have less access to depression care. The authors recommend targeted mental health programs and better access for vulnerable groups.
Simply put: More people are taking depression medicine, but some groups—like women, older adults, and people with disabilities—use it much more than others.
Abstract
BACKGROUND: Depression is a major public health concern, and antidepressant medication is commonly prescribed for its management. Understanding trends in antidepressant use across socio-demographic groups is crucial for targeted interventions. OBJECTIVE: To analyze trends in antidepressant medication use between 2019 and 2023 using data from the National Health Interview Survey (NHIS), focusing on demographic factors such as gender, age, race, and social vulnerability. METHOD: Data from the NHIS (2019-2023) were analyzed to assess trends in antidepressant use by sociodemographic variables. Descriptive statistics and trends were evaluated using prevalence estimates with confidence intervals. RESULT: <0.001). CONCLUSION: The study reveals a steady increase in antidepressant use from 2019 to 2023, particularly among females, older adults, and individuals with higher social vulnerability or disabilities. Racial disparities in antidepressant use persist, with White individuals showing the highest prevalence. These findings highlight the ongoing need for targeted mental health interventions, especially for vulnerable groups, and underscore the importance of addressing disparities in access to mental health care. Future research should focus on the factors driving these trends and their implications for public health.
Referenced In
Created: May 10, 2026