Summary
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1 Sample Definition And Size
The study enrolled initially 100 healthy premenopausal overweight Korean women aged 20–50 years with BMI ≥23 kg/m²; 84 completed the trial and were included in the analysis (Kim et al., 2015) ([sciencedirect.com](https://www.sciencedirect.com/science/article/pii/S0271531715000676?utm_source=openai)).
2 Study Type
Randomized controlled clinical intervention trial with three parallel groups: a no-diet control (Normal‑C), a pair‑fed placebo juice group (Positive‑C), and a lemon detox diet group (Lemon‑D) over an 11‑day intervention (7 days juice abstinence plus 4 days transition) ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/25912765/?utm_source=openai)).
3 Conflicts Of Interest
The study was supported by a research grant (2013‑RE01443) from Cencorp Korea Co. Ltd.; the funding arrangement was reviewed and approved by Seoul Women’s University per its objectivity policy ([sciencedirect.com](https://www.sciencedirect.com/science/article/pii/S0271531715000676?utm_source=openai)).
4 Results Summary
Compared to the Normal‑C group, both Lemon‑D and Positive‑C groups showed significantly greater reductions in body weight, BMI, percentage body fat, and waist‑hip ratio. Serum insulin, HOMA‑IR, leptin, and adiponectin decreased in both Lemon‑D and Positive‑C groups. Serum high‑sensitivity C‑reactive protein (hs‑CRP) decreased only in the Lemon‑D group. Hemoglobin and hematocrit remained stable in Lemon‑D but decreased in Positive‑C and Normal‑C groups ([pubmed.ncbi.nlm.nih.gov](https://pubmed.ncbi.nlm.nih.gov/25912765/?utm_source=openai)).