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Abstract

Coffee consumption has been shown to be associated with cancer of various sites in epidemiological studies. However, there is no comprehensive overview of the substantial body of epidemiologic evidence.We searched MEDLINE, EMBASE, Science Citation Index Expanded and bibliographies of retrieved articles. Prospective cohort studies were included if they reported relative risks (RRs) and corresponding 95% confidence intervals (CIs) of various cancers with respect to frequency of coffee intake. We did random-effects meta-analyses and meta-regressions of study-specific incremental estimates to determine the risk of cancer associated with 1 cup/day increment of coffee consumption.59 studies, consisting of 40 independent cohorts, met the inclusion criteria. Compared with individuals who did not or seldom drink coffee per day, the pooled RR of cancer was 0.87 (95% CI, 0.82-0.92) for regular coffee drinkers, 0.89 (0.84-0.93) for low to moderate coffee drinkers, and 0.82 (0.74-0.89) for high drinkers. Overall, an increase in consumption of 1 cup of coffee per day was associated with a 3% reduced risk of cancers (RR, 0.97; 95% CI, 0.96-0.98). In subgroup analyses, we noted that, coffee drinking was associated with a reduced risk of bladder, breast, buccal and pharyngeal, colorectal, endometrial, esophageal, hepatocellular, leukemic, pancreatic, and prostate cancers.Findings from this meta-analysis suggest that coffee consumption may reduce the total cancer incidence and it also has an inverse association with some type of cancers.

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RC Yu
a year ago

Coffee and Cancer

Cancer is all too prevalent, and is of course a leading cause of death. My family is no exception.

One highlight I came across – from this umbrella review of "coffee consumption and health" – is that drinking coffee seems to lower cancer risk.

The umbrella review highlighted results from this meta-analysis of 40 cohort studies , that found that drinking coffee is associated with an 18% lower risk of (any) cancer.

(Note: this is 18% lower "relative risk", not lower "absolute risk".)

But not for all cancer types, unfortunately.

Drinking coffee is associated with lower risk of: melanoma, leukaemia, and prostate, endometrial, oral, non-melanoma skin, liver, and lung cancers.

(A caveat: among smokers, those who drink more coffee seem to have higher mortality risks.)

But (sadly) there is no association between coffee consumption and: lymphoma, glioma, or gastric, colorectal, colon, rectal, ovarian, thyroid, breast, pancreatic, oesophageal, and laryngeal cancers.

Still – plus points for coffee!

0

Coffee and Cancer

Cancer is all too prevalent, and is of course a leading cause of death. My family is no exception.

Does drinking coffee reduce cancer risk?

This umbrella review of "coffee consumption and health" finds drinking coffee seems to lower cancer risk.

The umbrella review highlighted results from this meta-analysis of 40 cohort studies, that found that drinking coffee is associated with an 18% lower risk of (any) cancer.

(Note: this is 18% lower "relative risk", not lower "absolute risk".)

But not for all cancer types, unfortunately.

Drinking coffee is associated with lower risk of: melanoma, leukaemia, and prostate, endometrial, oral, non-melanoma skin, liver, and lung cancers.

(A caveat: among smokers, those who drink more coffee seem to have higher mortality risks.)

But (sadly) there is no association between coffee consumption and: lymphoma, glioma, or gastric, colorectal, colon, rectal, ovarian, thyroid, breast, pancreatic, oesophageal, and laryngeal cancers.

Still – plus points for coffee!

0